Fri Nov 28 2025

41 articles - From Friday Nov 21 2025 to Friday Nov 28 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Inflamm Bowel Dis
Clinical Significance of Mucin Signatures in Inflammatory Bowel Diseases: A Systematic Review of Their Expression Patterns, Polymorphisms, and Post-translational Modifications.

Together, these findings underscore the involvement of mucins in IBD and point to their potential as biomarkers for barrier dysfunction.

Pubmed   Journal   ReadQx 

J Crohns Colitis
Systematic Review and Network Meta-Analysis: Evaluating the Impact of advanced therapies for Moderate-to-Severe Ulcerative Colitis on Health-Related Quality of Life.

Advanced therapies vary in their impact on HRQoL, with some demonstrating clinically meaningful improvements in UC. These findings support integrating HRQoL into treatment selection and shared decision-making.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr
Comparison of Hemoglobin Measurements from Venous and Capillary Blood from the same individual using HemoCue 301 and Automated Hematology Analyzer in a cross-sectional Community-Based Study in India.

HC-C showed higher anemia prevalence and weaker agreement compared to AHA-V, indicating potential overestimation. Anemia prevalence estimated through capillary blood using POC devices in large-scale public health surveys needs cautious interpretation.

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Estimating Days Needed for Dietary Assessment in Pregnancy: A Modeling Study.

We provide a new approach to estimating required dietary days to inform future study design. Existing studies may be underpowered and cohort estimates may overstate individual-level accuracy.

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Healthful dietary patterns and risks of microvascular complications among individuals with type 2 diabetes: a prospective cohort study.

Higher healthful dietary pattern scores were associated with lower risk of DKD, whereas inverse associations with risks of DR and DN were mainly observed for HPDI. These associations were mainly mediated through pathways relating to renal function and inflammation.

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What Is "Healthy" Food? A Cross-Sectional Evaluation of Foods and Beverages Consumed by US Adults That Satisfy the US Food and Drug Administration's Updated "Healthy" Claim Criteria.

Findings suggest few foods met "healthy" criteria. Moderate correlations between "healthy" criteria, Nova, and validated nutrient profiling models provide evidence of convergent validity, yet underscore the challenge of classifying foods by healthfulness, and highlight uncertainty about whether discrepancies reflect real differences in model performance and food healthfulness.

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Inflamm Bowel Dis
A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease.

These findings underscore the potential of IEOs as a valuable model for studying IBD and offer key insights that could guide the development of targeted therapies for both monogenic and non-monogenic forms of IBD.

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Association of Geography With Screening and Development of Cervical Neoplasia in Those With Inflammatory Bowel Disease.

Similarities in screening between cases and controls suggest that lifestyle factors (eg, human papillomavirus vaccination, sexual history) may underpin the reduced odds of cervical cancer, rather than screening frequency. Efforts should be made to increase screening in immunosuppressed individuals.

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Differences in Anti-αvβ6 Integrin Antibody Expression between U.S. and Japanese Cohorts in Inflammatory Bowel Disease.

Anti-αvβ6 is a valuable biomarker for UC diagnosis. However, this study demonstrated differences in its behavior between U.S. and Japanese cohorts, particularly in CD. Cohort-informed interpretation and combined antibody testing may improve diagnostic precision and disease stratification in IBD.

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Mucosal B Cell Expansion and Maturation Contribute to Colitis Pathogenesis.

Our findings suggest that naive B cells expand in actively inflamed mucosa from UC patients and play a pathogenic role in experimental colitis.

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Safety and Efficacy of Ozanimod in Patients With Moderately to Severely Active Ulcerative Colitis Stratified by Age.

Here, we analyzed the impact of patient age on ozanimod safety and efficacy in TN and during the open-label extension (OLE). Methods Patients were stratified by age at TN baseline: 60 years of age.

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Serum and Histologic Eosinophilia as a Predictive Biomarker of Response to Mirikizumab in Ulcerative Colitis.

and relevance Baseline eosinophil levels may predict response to mirikizumab and guide early treatment decisions. These findings support a potential role for eosinophils as biomarkers in UC management.

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Shared Genetic Basis Between Systemic Lupus Erythematosus and Inflammatory Bowel Disease in East Asian Ancestry: A Genome-Wide Cross-trait Analysis.

The major histocompatibility complex region emerges as a critical hub for shared genetic correlations and pleiotropic effects in SLE-IBD pathogenesis. Gene-level enrichment analyses implicate chemokine and lipid binding as underlying shared biological mechanisms.

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Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease.

Short ileal MVL is associated with the development of complicated disease behaviors in pediatric CD, supporting the potential use of this histological phenotype as a biomarker for CD prognosis.

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J Crohns Colitis
Benefit-Risk Profile of Upadacitinib: Exploratory Post Hoc Analysis of Phase 2b/3 Studies in Patients With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease.

UPA resulted in consistent benefit versus placebo across CV risk, prior treatment failure, and age subgroups. No treatment differences were seen in AESIs across subgroups except herpes zoster and serious infections, reinforcing the favorable benefit-risk profile for UPA in CD and UC seen in the overall study populations. Clinical trial numbers NCT02819635, NCT03653026, NCT03345836, NCT03345849, NCT03345823.

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Development and validation of a novel multimodal deep learning model integrating histopathology, radiology, and clinical data to predict primary non-response to infliximab in patients with crohn's disease.

The study developed a multimodal deep learning model accurately predicting IFX primary non-response, offering a tool to guide individualized therapy and improve Crohn's disease outcomes.

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Economic Burden of Microscopic Colitis in Relation to Disease Activity: A Nationwide Cost-of-illness Study.

Compared with the general population, patients with MC had almost twice as high annual mean costs. Excess costs were particularly high in patients with a high disease activity at onset, mainly driven by work loss.

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From Resection to Preservation: Redefining the Surgical Paradigm in Crohn's Disease.

Surgery should no longer be viewed solely as a response to complications, but rather as an individualized, biology-driven strategy that prioritizes bowel preservation. In this rapidly advancing field, innovation is measured not only by clinical outcomes but also by every centimetre of bowel preserved.

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The Complex Relationship Between Physical Activity and Fatigue with Socioeconomic Status, and Mental Health Factors in Individuals with IBD.

Low SES was a main driver of engaging in low PA (and not high fatigue). Anxiety and/or depression and active disease were drivers of high fatigue (and not low PA).

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Liver Transpl
Liver retransplantation in the era of machine perfusion.

Liver retransplantation outcomes are superior when machine perfusion preservation is used compared to SCS. Machine perfusion should be considered in al cases undergoing liver retransplantation.

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Urinary cell cycle arrest proteins for early prediction and phenotyping of subclinical and clinical acute kidney injury after liver transplantation.

Subclinical patients with AKI (24%) had higher risks of acute kidney disease (42% vs 26%), early allograft dysfunction (32% vs 18%), graft loss (16% vs 4%), and longer intensive care unit stays. u[TIMP-2]*[IGFBP-7] is a valuable biomarker for early AKI risk stratification after liver transplantation, with subclinical AKI representing a distinct, clinically relevant phenotype.

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Pancreatology
Plasma fatty acids, genetic risk, and incident pancreatic cancer: A prospective cohort study.

Increasing plasma SFAs were associated with a higher risk of PC, whereas plasma PUFAs especially n-3 PUFAs were inversely associated with PC risk. The potential interaction between SFAs and genetic risk for PC warrants further investigation.

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Prevalence, clinicopathological features, and prognosis of diabetes in pancreatic cancer: A single-center retrospective cohort study of 1620 patients.

DM is common in PC and associates with distinct clinicopathological profiles. NODM is linked to jaundice and poorer survival, while DM status serves as an independent prognostic factor in the curative-surgery subgroup, with part of NODM's adverse effect operating through bilirubin.

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The impact of opioid use in chronic pancreatitis from 2004-2024: A propensity-matched analysis of 183,214 individuals.

Opioid use in chronic pancreatitis is associated with higher morbidity, mortality, and healthcare utilization, likely reflecting underlying disease severity and complications. These patients represent a high-risk group warranting greater attention, and prospective studies are needed to clarify causal relationships and guide optimized pain management strategies.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr
Steps toward better understanding the role of dietary intake on development of complications in people with type 2 diabetes.

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Inflamm Bowel Dis
Artificial Intelligence as a New Player in Dietary Management of Inflammatory Bowel Disease.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis
CAPTURE IBD: Advancing Precision Medicine in Pediatric IBD.

Pubmed   Journal   ReadQx 

Exploring the EPIcenter of VEOIBD: Defining the Genetic Drivers of Intestinal Epithelial Cellular Dysfunction.

Pubmed   Journal   ReadQx 

J Crohns Colitis
Beyond the Mucosa: Intestinal Ultrasound for Post Endoscopic Healing Risk Stratification in Ulcerative Colitis-Authors' Reply.

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Liver Transpl
Beyond sex: Sarcopenia as the missing link in MELD score disparities and the case for cystatin C.

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Frailty in early HCC transplant candidates: It's not only about the tumor.

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Liver Transplant using the RAPID technique in a patient with colorectal liver metastases: Case report of a first in the United States.

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Pancreas
The Challenge of Pancreatic Duct Cannulation in Chronic Pancreatitis.

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Pancreatology
Collective evidence for solid pseudopapillary neoplasm of the pancreas as a hormone-dependent tumor.

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Future of fluid therapy for acute pancreatitis.

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PanSCOPE - Pancreatic cancer signature COllection for prognostic evaluation.

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Letters&Replies

Letters to the editors and authors’ replies

Am J Clin Nutr
Genotype-informed magnesium supplementation and rectal-niche microbial shifts: clarifying multiplicity, compositionality, and local vitamin D biology.

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Reducing dietary fat and cholesterol is clinically important to maintain or lower serum LDL cholesterol concentrations to optimal levels.

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Pancreatology
Complete pathological response in metastatic pancreatic adenocarcinoma following neoadjuvant therapy.

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Pancreatic cancer risk in genetically determined chronic pancreatitis.

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Response to Letter to the Editor: "Bariatric surgery in pancreatic cancer: The double-edged sword of metabolic benefits and diagnostic challenges".

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